FITC标记的选择性剪接因子3亚基1抗体
产品名称: FITC标记的选择性剪接因子3亚基1抗体
英文名称: Anti-SF3A1/FITC
产品编号: HZ-19676R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SF3A1/FITC Conjugated antibody
FITC标记的选择性剪接因子3亚基1抗体
英文名称 | Anti-SF3A1/FITC |
中文名称 | FITC标记的选择性剪接因子3亚基1抗体 |
别 名 | Pre mRNA processing 21; Pre mRNA splicing factor SF3a; PRP21; PRPF21; SAP 114; SAP114; sf3a1; SF3A1_HUMAN; SF3A120; Spliceosome associated protein 114; Spliceosome-associated protein 114; Splicing factor 3 subunit 1; Splicing factor 3a subunit 1 120kDa; Splicing factor 3a subunit 1. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 89kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SF3A1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing. [provided by RefSeq, Aug 2014] Function: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Subunit: Nucleus. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 2 SURP motif repeats. Contains 1 ubiquitin-like domain. Database links: Entrez Gene: 10291 Human Entrez Gene: 67465 Mouse Omim: 605595 Human SwissProt: Q15459 Human SwissProt: Q8K4Z5 Mouse Unigene: 406277 Human Unigene: 505597 Human Unigene: 156914 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码剪接因子3A蛋白复合物的亚基。剪接因子3A异三聚体是成熟的U2小核糖核蛋白颗粒(SNRNP)的一个组成部分。U2小核糖核蛋白在剪接体组装和mRNA前体剪接中起关键作用。[ RefSeq,Aug 2014提供]