FITC标记的CD39样蛋白2/ENTPD6抗体
产品名称： FITC标记的CD39样蛋白2/ENTPD6抗体
英文名称： Anti-ENTPD7/FITC
产品编号： HZ-14603R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ENTPD7/FITC Conjugated antibody
FITC标记的CD39样蛋白2/ENTPD6抗体
| 英文名称 | Anti-ENTPD7/FITC |
| 中文名称 | FITC标记的CD39样蛋白2/ENTPD6抗体 |
| 别 名 | DKFZp667O124; Ectonucleoside triphosphate diphosphohydrolase 7; ENTPD 7; ENTPD7; ENTP7_HUMAN; LALP 1; LALP1; Lysosomal apyrase like protein 1; NTPDase 7; NTPDase7. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 69kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ENTPD7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: LALP1 is a 604 amino acid multi-pass membrane protein that belongs to the GDA1/CD39 NTPase family. Preferentially hydrolyzing nucleoside 5’-triphosphates, LALP1 and has an order of activity with respect to possible substrates, which is UTP > GTP > CTP. The gene that encodes LALP1 consists of approximately 51,740 bases and maps to human chromosome 10q24.2. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. Function: The ENTPD7 belongs to the GDA1/CD39 NTPase family and the gene resides on chromosome 10q23-q24 and contains 12 exons and 11 introns covering a genomic region of approximately 46 kilobase pairs. The subcellular localization and enzymatic activity of ENTPD7 indicated that ENTPD7 is indeed an endo-apyrase with substrate preference for nucleoside triphosphates UTP, GTP, and CTP. Subcellular Location: Cytoplasmic intracellular multi-pass membrane protein. Localizes to vesicular compartments. Similarity: Belongs to the GDA1/CD39 NTPase family. Database links: Entrez Gene: 57089 Human Entrez Gene: 93685 Mouse Entrez Gene: 309390 Rat SwissProt: Q9NQZ7 Human SwissProt: Q3TCT4 Mouse Unigene: 716513 Human Unigene: 296789 Mouse Unigene: 169265 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Lalp1是一种604氨基酸多通道膜蛋白，属于GDA1/CD39 NTPASS家族。优选水解核苷5’-三磷酸盐，LALP1，对可能的底物具有活性顺序，即UTP>GTP>CTP。编码Lalp1的基因由大约51740个碱基组成，并映射到人类染色体10q24.2。染色体10跨越了近1.35亿个碱基对，约占细胞总DNA的4.5%，编码近1200个基因。一些基因定位在10号染色体上的缺陷与Charcot-Marie Tooth病、Jackson-Weiss综合征、Usher综合征、非综合征性耳聋、Wolman综合征、Cowden综合征、多发性内分泌肿瘤2型和卟啉症有关。